A new study suggests that heartburners and proton pump inhibitors like Prilosec, Nexium, and others may be responsible for a significant number of heartburn episodes.
In a new study, researchers at the University of California, San Francisco, found that those who took omeprazole for a prolonged period of time before the onset of heartburn had a lower risk of hospitalization, compared with those on a similar dose of a placebo.
The study, presented at the American Heartburn Society annual meeting in September in San Francisco, examined the health care of people with heartburn at the California Department of Public Health, and concluded that omeprazole reduced hospitalizations and hospitalizations for heartburn and proton pump inhibitors by as much as 55% compared with the placebo group.
The results, which were presented at the American Heartburn Society annual meeting in September, were published in the journal, which highlights the importance of ongoing research and clinical trials to help inform the development of new drugs for heartburn.
Researchers studied over 2,000 people with heartburn at the state's San Francisco Bay Area hospital between the years of 2003 and 2018 and found that omeprazole was significantly more effective than other proton pump inhibitors for reducing heartburn episodes, compared with the placebo group.
AstraZeneca is now working with the U. S. Food and Drug Administration to approve a new, cheaper and more effective alternative for heartburn, called Nexium.
"It has always been our hope that when these drugs are approved and used in a clinical setting it will help save lives," said lead researcher, Dr. Andrew Witty, from the University of Minnesota. "But it is hard to believe that we are at a moment when that hope has been crushed."
In the U. S., Prilosec is known as a proton pump inhibitor and is used to treat symptoms of acid reflux, which are caused by excess stomach acid. Nexium is also used to treat ulcers and indigestion.
The study is funded by AstraZeneca.
The study was the first to compare omeprazole with other acid blockers, including proton pump inhibitors like Prevacid and Prilosec.
Omeprazole, which is also sold under the brand name Nexium, is also available in generic forms. Prevacid was approved by the U. Food and Drug Administration in 1999, and Prilosec in 2003. The study was conducted in a hospital in California.
The study was published online in the journal. AstraZeneca will continue to work with the FDA and other regulatory bodies to approve generic versions of omeprazole for sale.
Prilosec is a type of proton pump inhibitor called a proton pump inhibitor, or PPIs, and is used to treat symptoms of acid reflux, a chronic condition in which the stomach acid leaks back into the esophagus.
"As a result, proton pump inhibitors like omeprazole can have a very positive impact on quality of life for people who are at high risk for heartburn," said lead study author Dr.
Dr. William Wigmore, from the University of Minnesota, also said that omeprazole, a proton pump inhibitor used to treat ulcers and indigestion, may help people who are at risk for heartburn. The medication, which is not approved by the FDA to treat acid reflux, can also help prevent heartburn.
Wigmore is the clinical research fellow and lead author on the study.
"Our results show that omeprazole reduces hospitalizations for heartburn and is effective at reducing hospitalizations for heartburn that are associated with an increased risk of heartburn."
The study was presented at the American Heartburn Society annual meeting in September in San Francisco. The study is the first to compare omeprazole with proton pump inhibitors like Prilosec and Nexium.
Donald R. Leckrone, from the University of California at San Francisco, said that omeprazole was a breakthrough in medicine, but that there was still much more work to do to find the best treatment for people's heartburn.
"The evidence is still not in the favor of omeprazole, so we are not sure what will work for each patient," said Leckrone, who is also lead investigator for the study.
Nexium 24HR is a widely used medication for the treatment of proton pump inhibitors (PPIs) as it provides long-lasting relief. Here is the scoop on Nexium 24HR.
Nexium 24HR is primarily used to treat acid reflux (such as heartburn, indigestion, and stomachaches) and gastroesophageal reflux disease (GERD). It is important to note that Nexium 24HR should only be taken when needed as it can cause potential gastric ulceration and possibly delayed healing.
The benefits of Nexium 24HR include:
It's important to note that Nexium 24HR should only be taken if required as it can cause potential gastric ulceration and possibly delayed healing, which can exacerbate existing conditions like GERD.
Like any medication, Nexium 24HR can cause side effects, although not everyone experiences them. The most common side effects include:
It's crucial to discuss any concerns or potential side effects with your healthcare provider, as they will guide you through this process effectively.
The cost of Nexium 24HR is not a concern for many insurance plans as it offers affordable and convenient options for managing prescription drug costs. However, factors like cost can influence the price of Nexium 24HR, including generic alternatives and pharmacy discounts.
The cost of Nexium 24HR can vary based on individual policies and specific circumstances. Some plans cover up to 90% of the cost, while others may require coverage beyond that. It's essential to check individual insurance plans to understand the coverage of Nexium 24HR as well as the coverage details for specific medications like proton pump inhibitors.
It's important to have open communication with your healthcare provider to determine if Nexium 24HR is the right treatment for you. Regular check-ups can help monitor side effects and adjust the dosage accordingly.
Nexium 24HR provides long-lasting relief for acid reflux episodes, offering individuals the relief they need as treatment becomes more effective. However, it's crucial to consult with a healthcare provider before starting any medication regimen to ensure it aligns with your health needs. By understanding the cost of Nexium 24HR, comparing it to other proton pump inhibitors like Protonix and esomeprazole, and exploring generic alternatives, you can ensure that you are getting the best value for your medication.
Nexium 24HR Once Daily Dosing Tablets provide lasting relief from frequent heartburn and acid reflux.
Nexium 24HR 20mg esomeprazole tablets are for the lasting symptomatic relief of frequent heartburn, acid regurgitation and other symptoms associated with gastro-oesophageal reflux
Carefully read the enclosed Consumer Medicine Information before use.
AUST R NUMBER:231439
Lactose
INGREDIENTS:Each tablet contains: Esomeprazole 20mg (as Magnesium Trihydrate).
Do not use:- for children under 18 years of age.- if allergic to esomeprazole.- if allergic to any other proton pump inhibitor (omeprazole, rabeprazole, lansoprazole, pantoprazole).- if you are taking antiretroviral medicines, such as atazanavir.- if you are taking cilostazol a medicine used to treat pain and/or cramping in the lower leg (or arms) due to inadequate blood flow to the muscles.- if you are breastfeeding or intend to breastfeed.- -f you are experiencing weight loss, persistent regurgitation of food or vomiting, difficulty swallowing or symptoms of gastro-intestinal bleeding, except on medical advice- if you are pregnant or intend to become pregnant except on the advice of a doctor or pharmacist- if the expiry date printed on the pack has passed. Ask your pharmacist or doctor before use if you:- have or ever have had serious liver disease.- are taking digoxin (a medicine used to treat heart problems).- are taking ketoconazole (a medicine used to treat fungal infections)- are taking clopidogrel or warfarin (medicines used to stop the blood clotting)- are taking other medicines regularlyThis preparation is for the relief of minor and temporary ailments and should be used strictly as directed. Do not use for any purpose other than what is specified on the pack, except on doctor's advice. Keep to recommended dose. If an overdose is taken or suspected telephone your doctor or the Poisons Information Centre (Australia 13 11 26, or New Zealand 0800 764 766) or go to the Accident and Emergency department at your nearest hospital. Tell your pharmacist or doctor if you do not feel well, if new or additional symptoms occur while you are taking Nexium 24HR Once Daily Dosing.
ONLINE MANDATORY STATEMENT:Always read the label and follow the directions for use.
Puerto Rico, US
Alli PharmaceuticalsNoticehttp://www.hpf.com/search/search.asp=Nexium-24HR- Once- Daily DosingStrength | |
---|---|
Esomeprazole 20mg | 20 mg |
Magnesium Trihydrate 40mg | 4 mg |
Esomeprazole 40mg | 8 mg |
Nitrofurantoin, Nexium 14 Capsules
Nexium is used to treat infections of the urinary tract, intestinal tract, respiratory tract, genital tract, chest, and nasal tracts. It can also be used to treat certain sexually transmitted infections such as gonorrhoea. This product does not contain sodium. Do not use if allergic to Nexium or any of the ingredients listed at the end of the packaging or if you are having any symptoms of allergy (such as difficulty breathing, chest pain, or palpitations) or chest pain such as sudden shortness of breath or chest pain that gets worse.IMPORTANT NOTE:The product in the package is for external use only. You are advised to take Nexium exactly as described in this package. If you are using a stronger dose of Nexium you should wait at least 2 weeks after the last dose to take the dose. If you have taken Nexium for 12 weeks or longer, you should consult your doctor. The expiry date printed on the pack to be taken is the first day before the day it is DURING use. This product has been tested for effectiveness in treating malaria and is not recommended for use in children under 12 years of age. Consult your doctor or pharmacist for more information.
Read moreIncluded this break in product information:
Nexium 14 Capsules
Product Description: Nexium is used to treat infections of the urinary tract, intestinal tract, respiratory tract, genital tract, chest, and nasal tracts. Do not use if allergic to Nexium or any of the ingredients listed at the end of the packaging or if you are having any symptoms of allergy (such as difficulty breathing, chest pain, or palpitations)The expiry date printed on the pack is the first day before the day the product is DURING use.PRECAUTIONS:Do not take Nexium if you are allergic to any of the ingredients listed at the end of this leaflet. If you are having any symptoms of an allergic reaction such as trouble breathing, chest pain, or palpitations, immediately stop taking the medicine and contact your doctor. Do not use Nexium if you are having any problems with the heart, blood vessel, liver, kidney, or lung. This medicine can cause dizziness and drowsiness when taking it. Do not use Nexium if you are taking digoxin, if you have any kidney problems, if you have asthma or if you have porphyrias (an overgrowth of thyroid tissue in the lungs) if you are on any other medicine, if you are in the last 3 months of pregnancy, if you are taking any other medicine, and if you are in the first 6 months of pregnancy. This medicine should NOT be taken during the last 6 months of pregnancy. Consult your doctor if you are pregnant or think you may be pregnant. Before taking Nexium, tell your doctor if you are taking any other medicines, including medicines that can cause nausea, weight gain or drowsiness, as these may be signs of an overactive thyroid, thyroid cancer, thyroid problems, or if you are on any other medication. You may need to take Nexium during the first 6 months of pregnancy.